Afatinib is a targeted therapy medicine used to treat certain types of non-small cell lung cancer (NSCLC). It is a type of tyrosine kinase inhibitor (TKI) that works by blocking certain proteins that help cancer cells grow. Afatinib is taken orally, typically once a day, and can be used to treat NSCLC that has spread to other parts of the body (metastatic NSCLC) in people with certain types of genetic changes. It may also be used as an initial treatment for some people with advanced NSCLC who have not yet received chemotherapy.
Afatinib, sold under the brand name Gilotrif, is a prescription medication used to treat a specific type of non-small cell lung cancer (NSCLC). Here's a detailed description:
What it treats:
- NSCLC is the most common type of lung cancer, and Afatinib specifically targets EGFR-mutated NSCLC.
- EGFR (epidermal growth factor receptor) is a protein that plays a role in the growth and division of cancer cells. Afatinib targets mutations in this protein, helping to slow or stop the growth of cancer cells.
How it works:
- Afatinib belongs to a class of drugs called tyrosine kinase inhibitors (TKIs).
- TKIs work by blocking the activity of certain enzymes, including EGFR.
- By blocking EGFR, Afatinib disrupts the signals that tell cancer cells to grow and divide, hindering their progression.
Dosage and administration:
- Afatinib comes as tablets taken orally, usually once a day on an empty stomach.
- It's crucial to follow the exact dosing instructions provided by your doctor, and avoid taking more or less than prescribed.
Potential side effects:
- Afatinib can cause various side effects, including:
- Skin problems: Dryness, rash, acne-like eruptions
- Digestive issues: Diarrhea, nausea, vomiting, mouth sores
- Fatigue
- Eye problems: Dry eyes, blurred vision
- Changes in hair and nails
Important information:
- Afatinib is not suitable for everyone and may interact with other medications you are taking.
- It's important to disclose your medical history to your doctor before starting Afatinib, especially if you have any pre-existing health conditions.
- Pregnancy and breastfeeding are contraindicated with Afatinib due to potential risks to the developing baby or infant.
Remember:
- Afatinib is a powerful medication and should only be taken under the supervision of a qualified healthcare professional.
- If you experience any concerning side effects, consult your doctor immediately.
- Do not hesitate to ask your doctor any questions you may have regarding Afatinib or your treatment plan.