Citric acid esters of mono- and diglycerides of fatty acids

International Numbering System (INS) for Food Additives: 

Food additives Europe numbers;  E472c 

Citric acid esters of mono- and diglycerides of fatty acids (also known as Citrem or E 472c) is not exactly a medical substance. It falls under the category of food additives, specifically an emulsifier. Here's a breakdown:

  • Function in Food: An emulsifier helps to blend ingredients that wouldn't normally mix together, like oil and water. This is crucial in creating the texture and stability of many processed foods.
  • Composition: Citrem is made by reacting citric acid (found in citrus fruits) with mono- and diglycerides (fats derived from vegetable oils). It may also contain small amounts of other related molecules.
  • Properties:
    • Can be liquid, solid, or a white to pale yellow powder.
    • May have a mild vinegar odor.
    • Disperses or dissolves in oils and fats, but not water.
  • Applications in Food:
    • Found in various processed foods like baked goods, whipped cream, margarine, and salad dressings.
    • Helps create a smooth texture, prevents separation of ingredients, and improves shelf life.

Safety as a Food Additive:

  • Generally recognized as safe (GRAS) for consumption by regulatory bodies like the FDA and JECFA (Joint FAO/WHO Expert Committee on Food Additives).

Important Considerations:

  • While considered safe in general, some studies suggest a possible link between high intake of certain types of emulsifiers (like some lactic acid esters of mono- and diglycerides) and an increased risk of cardiovascular disease. More research is needed to confirm this specifically for Citrem.

In Conclusion:

Citric acid esters of mono- and diglycerides of fatty acids is a food additive, not a medical substance. It's used in various processed foods to improve texture and stability. If you have concerns about food additives or Citrem specifically, it's always best to consult a doctor or registered dietitian.