Dextranomer

Dextranomer is a type of polysaccharide derived from the bacterial species Leuconostoc mesenteroides. It is used in a variety of medical applications, including wound healing, tissue engineering, drug delivery, and as a component of injectable hydrogels. Dextranomer is primarily composed of a linear chain of glucose molecules and is highly biocompatible and biodegradable. Its unique properties allow it to maintain its structure in the body while gradually being absorbed. As a result, it acts as a protective barrier and promotes tissue regeneration. Dextranomer is also used as a binder in pharmaceutical tablets and as an excipient in parenteral formulations.

Dextranomer is a synthetic, man-made substance used in various medical applications. It's a type of polysaccharide, a complex sugar molecule, specifically made from cross-linked dextran polymer chains. These chains form a three-dimensional network that gives dextranomer its unique properties .

Here's a breakdown of its two main uses:

  • Wound healing: Dextranomer is a key ingredient in some wound dressing products. It absorbs fluids from the wound bed, creating a moist environment that promotes healing. Brand names like Debrisan and Exudex are some examples
  • Fecal incontinence treatment: Dextranomer, combined with hyaluronic acid, is used as an injectable gel for treating fecal incontinence. The gel is bulked up the tissues around the anus, improving bowel control. Solesta is a brand name for this application .
  • It's important to note that dextranomer is always used under a doctor's supervision. Depending on the application, it may be applied topically to a wound or injected into specific areas.


 

Anatomical Therapeutic Chemical Classification
D - Dermatologicals
D03 Preparations for treatment of wounds and ulcers
D03A - Cicatrizants
D03AX Other cicatrizants
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