Erenumab is a prescription medicine used to prevent migraine headaches in adults. It is thought to work by blocking the receptor for calcitonin gene-related peptide (CGRP), a molecule that is involved in migraine attacks. It is given as an injection under the skin (subcutaneously) once a month. It is the first monoclonal antibody approved to treat migraine and is approved for those who have at least four migraine days per month.
Erenumab, also known by the brand name Aimovig, is a prescription medication used to prevent migraine headaches [FDA]. Here's a closer look at its key features:
- Type of medication: Monoclonal antibody [National Institutes of Health].
- Function: Erenumab works by targeting a molecule called calcitonin gene-related peptide (CGRP) which is thought to play a role in migraine headaches [American Migraine Foundation]. By blocking CGRP, Erenumab can help prevent migraines from occurring.
Treatment:
- Erenumab is used for prophylaxis (prevention) of migraines in adults who experience frequent migraine attacks, typically defined as four or more migraine headaches per month [Mayo Clinic].
- It is administered as a self-injection under the skin (subcutaneous injection) typically once a month [WebMD].
Important things to know:
- Erenumab is a relatively new medication and long-term effects are still being studied [Mayo Clinic].
- It can cause side effects like injection site reactions, headache, constipation, and fatigue [WebMD].
- Erenumab is not suitable for everyone, particularly those with a history of allergic reactions to the medication or its components [Mayo Clinic].
- It is also not recommended for pregnant or breastfeeding women [Mayo Clinic].
Here are some resources for further information:
- FDA: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/761077s009lbl.pdf
- National Institutes of Health: https://pubmed.ncbi.nlm.nih.gov/30793254/
- American Migraine Foundation: https://americanheadachesociety.org/news/erenumab-safe-efficient-prophylactic-episodic-migraine/
- WebMD: https://www.webmd.com/drugs/2/drug-175275/aimovig-autoinjector-2-pack-subcutaneous/details
- Mayo Clinic: https://www.mayoclinic.org/drugs-supplements/erenumab-aooe-subcutaneous-route/description/drg-20443746
Disclaimer: I am unable to provide medical advice. If you have any questions about Erenumab or its use in relation to your migraines, please consult a doctor.