Gadoteric acid (also known as gadoterate meglumine or DOTAREM) is a contrast agent used in magnetic resonance imaging (MRI) to enhance the visibility of certain tissues or lesions. It works by shortening the time it takes for the MRI signal to decay, allowing for better imaging of those tissues. Gadoteric acid is a type of paramagnetic contrast agent, meaning it has an affinity for magnetic fields. It is FDA-approved and safe for use in adults and children.
Gadoteric acid, also commonly referred to by its salt form gadoterate meglumine, is a medication used during MRI scans as a contrast agent [1]. Here's a breakdown of its key points:
- Function: Improves image clarity in MRI scans by affecting how water molecules behave within the body [1, 2]. This allows doctors to better visualize specific areas, particularly those with abnormal blood flow or disrupted blood-brain barrier.
- Applications: Primarily used for MRI imaging of the brain, spine, and surrounding tissues in adults and children (including neonates) [2].
- Form: Administered intravenously (through a vein) as an injection [1, 2].
- Brand Names: Dotarem is one of the common brand names, but there may be others [1].
- Safety: Generally well-tolerated, but there are potential side effects, especially in patients with allergies or kidney problems [2, 6]. Doctors will weigh the risks and benefits before administering gadoteric acid.
Here are some additional resources you may find helpful:
- DrugBank: Gadoteric acid: Uses, Interactions, Mechanism of Action | DrugBank Online: [invalid URL removed]
- Wikipedia: Gadoteric acid - Wikipedia: en.wikipedia.org/wiki/Gadoteric_acid
Anatomical Therapeutic Chemical Classification
V - Various
V08 Contrast media
V08C - Magnetic resonance imaging contrast media
V08CA Paramagnetic contrast media
ATC Code
External Links
Gadoteric acid