Iopentol is an injectable X-ray contrast agent used to improve the visibility of organs and tissues in X-ray imaging. It is used during a variety of procedures, such as computed tomography (CT) scans, angiograms, and magnetic resonance imaging (MRI). Iopentol contains the active ingredient iohexol, a non-ionic, low-osmolar radiographic contrast agent, and is used to enhance the contrast of certain structures during imaging procedures. It is commonly used to visualize the cardiovascular system, including the coronary arteries, the aorta, and the veins in the abdomen.
Iopentol was a pharmaceutical drug previously used as a radiocontrast agent in X-ray imaging procedures, primarily in Europe [1]. Here's a breakdown of what we know about Iopentol:
Function:
- Radiocontrast agent: Iopentol contains iodine atoms, which readily absorb X-rays. This increased absorption creates a higher contrast between tissues in X-ray images, allowing doctors to see specific areas more clearly [1, 2].
Properties:
- Type: Iopentol is an iodine-containing, water-soluble agent [1].
- Osmolality: It's considered a low-osmolality contrast agent. Osmolality refers to the concentration of particles in a solution; lower osmolality is generally associated with fewer side effects compared to high-osmolality contrast agents [2].
Applications:
- Iopentol was used for various X-ray imaging procedures, likely similar to other contrast agents used today for angiography, CT scans, and examinations of body cavities [1].
Current Status:
- Iopentol is not as widely used today. Clinical trials suggest it produces high-quality images and is well-tolerated, but other contrast agents may be preferred [2, 3].
Here are some additional details you might find helpful:
- Trade Name: Imagopaque [1].
- Routes of administration: Intravenous, oral, and injection into body cavities [1].
- Elimination half-life: Around 2 hours after intravenous administration [1].