Omalizumab is a medication used to treat severe allergic asthma in adults and children over 12 years old. It is a monoclonal antibody that works by binding to certain antibodies in the body (IgE) and blocking their effects. This helps to reduce symptoms like wheezing and shortness of breath. It is also used to treat chronic idiopathic urticaria, a condition that causes hives and itching. Omalizumab is injected under the skin once a month and is usually given in combination with other medications for asthma.
Omalizumab, sold under the brand name Xolair, is a prescription medication used to treat several allergic conditions. Here's a breakdown of its key points:
Type of drug: Monoclonal antibody
Brand name: Xolair
Applications:
- Moderate-to-severe persistent allergic asthma: It helps manage symptoms in adults and children (6 years and older) whose asthma is not adequately controlled with inhaled corticosteroids.
- Chronic rhinosinusitis with nasal polyps (CRSwNP): This medication is used in adults (18 years and older) when other treatments like nasal corticosteroids haven't been effective.
- Food allergy: Omalizumab can help reduce the risk of severe allergic reactions in individuals (1 year and older) with certain food allergies, but it should not replace avoiding the allergenic food completely.
- Chronic spontaneous urticaria (CSU): This medication helps manage hives (hives without a known cause) in adults (12 years and older) when antihistamines haven't provided adequate relief.
How it works: Omalizumab targets a specific molecule called immunoglobulin E (IgE), which plays a crucial role in the allergic response. By binding to IgE, it prevents it from triggering the release of inflammatory substances, thereby alleviating allergic symptoms.
Important considerations:
- Omalizumab is administered through injection, typically in a healthcare setting.
- It's crucial to note that Omalizumab does not work for sudden asthma attacks and should not be used as an emergency treatment.
- It requires a prescription from a qualified healthcare professional and should be used under their guidance.