Orlistat

Orlistat is a drug used for weight loss. It works by preventing the body from absorbing some of the fat that is consumed in the diet. It is intended for use in conjunction with a reduced-calorie diet and increased physical activity. It is available as a prescription and over-the-counter (OTC) medication.

Orlistat is a medication used to aid weight loss and management. Here's a breakdown of its key features:

  • Function: Blocks fat absorption from food
  • Class: Lipase inhibitor
  • Medical use:
    • In conjunction with a reduced-calorie diet and exercise program for weight loss in overweight adults, including those with weight-related health problems like high blood pressure or diabetes.
    • To help prevent weight regain after successful weight loss.

How Orlistat Works:

  • Dietary fats need to be broken down into smaller pieces for your body to absorb them.
  • Orlistat works by blocking enzymes (lipases) in your stomach and intestines that break down fats.
  • With these enzymes blocked, some of the fat you eat isn't absorbed and passes out of your body in your stool.

Important things to know about Orlistat:

  • It should be used along with a doctor-approved diet and exercise plan for optimal results.
  • Orlistat doesn't block the absorption of calories from sugar or other non-fat foods, so maintaining a calorie deficit is still crucial.
  • Orlistat can cause side effects, most commonly related to the digestive system, like oily stools, gas, and cramping. These effects are usually more frequent at the beginning of treatment and may lessen over time.
  • Orlistat may reduce the absorption of some fat-soluble vitamins (A, D, E, and K). Taking a daily multivitamin containing these vitamins is recommended while on Orlistat.
Anatomical Therapeutic Chemical Classification
A - Alimentary tract and metabolism
A08 Antiobesity preparations, excluding diet products
A08A - Antiobesity preparations, excluding diet products
A08AB Peripherally acting antiobesity products
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