Perampanel is a prescription medication used to treat seizures associated with epilepsy. It works by blocking certain receptors in the brain that are involved in the development of seizures. Perampanel is usually taken once daily as a tablet. Common side effects of Perampanel include dizziness, drowsiness, headache, and fatigue.
Perampanel, sold under the brand name Fycompa, is a medication used as an adjunctive therapy to treat certain types of seizures in people aged 12 years and older [1, 2]. This means it's typically prescribed alongside other seizure medications, not by itself. Here's a closer look at perampanel:
Conditions treated:
- Partial-onset seizures: These seizures start in one specific part of the brain and may or may not spread to other areas [3].
- Primary generalized tonic-clonic seizures (grand mal seizures): These seizures involve a loss of consciousness and stiffening of the body, often with muscle jerking [3].
How it works: The exact way perampanel works in the brain to control seizures is not fully understood [2]. However, it's known to target glutamate receptors, which are involved in nerve cell communication in the brain. By affecting these receptors, perampanel is thought to help reduce excessive excitatory activity that can lead to seizures [2].
Dosage and administration: Perampanel comes in tablet form and is typically taken once daily at bedtime [1]. The dosage is gradually increased over time as determined by your doctor.
Important considerations:
- Perampanel may cause side effects, including dizziness, drowsiness, headache, fatigue, and mood changes [1]. It's important to talk to your doctor about any side effects you experience.
- Perampanel can interact with other medications, so it's crucial to tell your doctor about all the medications you're taking before starting perampanel [1].
- Perampanel may not be suitable for everyone, particularly those with certain mental health conditions or a history of suicidal thoughts [1].