Profenamine is a brand-name version of the drug meclizine, which is an antihistamine and anticholinergic used to treat nausea, vomiting, and dizziness associated with motion sickness. It is also used to treat vertigo and other symptoms of inner ear disorders. Profenamine is available in tablet and chewable tablet form and is taken orally. It is important to follow your doctor's instructions when taking Profenamine and to avoid taking larger doses than recommended.
Profenamine is a medication with a complex history. Here's a breakdown of what we know:
Current Status:
- Profenamine is not a widely used medication today.
- It has largely been replaced by safer and more effective medications for its intended purposes.
Historical Uses:
- Profenamine belonged to a class of medications called amphetamine derivatives.
- It was once used for a variety of purposes, including:
- Treating attention deficit hyperactivity disorder (ADHD)
- Addressing narcolepsy (sleep disorder causing excessive daytime sleepiness)
- Suppressing appetite
Reasons for Reduced Use:
- Profenamine has limitations that led to its decline in use:
- High potential for addiction and abuse: Similar to other amphetamines, profenamine has a high potential for misuse and dependence.
- Side effects: It can cause a number of side effects, including anxiety, insomnia, heart palpitations, and psychosis at high doses.
- Less effective alternatives: Safer and more effective medications have been developed for ADHD, narcolepsy, and weight management.
Safer Alternatives:
- Methylphenidate and amphetamines are now the preferred medications for ADHD, while modafinil is commonly used for narcolepsy.
- For weight management, lifestyle changes and other medications with a better safety profile are generally recommended.
Anatomical Therapeutic Chemical Classification
N - Nervous system
N04 Anti-parkinson drugs
N04A - Anticholinergic agents
N04AA Tertiary amines
ATC Code
External Links
Profenamine