Prussian blue

Prussian blue is a dark blue pigment that was developed in Berlin, Germany in the early 1700s. It was the first modern synthetic pigment. It is an inorganic compound made up of iron and cyanide, and has been used in paints, printing inks, and dyes. It is also used in medical and scientific applications, such as to detect certain metals in the body and to treat certain medical conditions. Prussian blue is a very stable pigment, and it has been used in art and architecture for centuries.

Prussian blue is interesting because it has two main uses: as a pigment and in medicine [1, 2]. Here's a breakdown of its medical applications:

Medical Use:

• Antidote: Prussian blue is used as a medication to help eliminate radioactive caesium and thallium from the body [1, 2]. These can be ingested through contaminated food or water or inhaled during a radiation emergency.
• How it Works: Prussian blue acts by binding to cesium and thallium in the intestines, preventing them from being absorbed into the bloodstream. The radioactive materials are then eliminated in stool [2].
• Administration: Prussian blue is typically given by mouth as tablets or through a nasogastric tube [2].

Important Points:

• Prussian blue is included in the World Health Organization's Model List of Essential Medicines [3]. This list contains medications considered to be the most effective and safe for meeting the needs of a health system.
• It should only be taken under the supervision of a medical professional following radiation exposure or thallium poisoning. People should not take artist's Prussian blue in an attempt to treat themselves [2].

Other Use (for reference):

• Prussian blue is also a very old and well-known pigment. It's valued for its deep blue color and has been used by artists for centuries [1].