Sevelamer

Sevelamer is a phosphate binder that is used to reduce the amount of phosphorus in the blood of people with kidney disease. It works by binding to the phosphorus in food and preventing it from being absorbed in the intestines. Sevelamer is used to lower high levels of phosphorus in the blood (hyperphosphatemia) in people with chronic kidney disease. It can help slow the progression of kidney disease, reduce the risk of cardiovascular disease, and reduce the risk of bone disease.

Sevelamer is a medication used to manage high blood phosphate levels in adults with chronic kidney disease (CKD). Here's a closer look at how it works and what to know about it:

Function:

• Phosphate Binder: Sevelamer works by binding to dietary phosphate in the intestine. This prevents the phosphate from being absorbed into the bloodstream and helps to lower overall blood phosphate levels.

Applications:

• Chronic Kidney Disease (CKD): In individuals with CKD, the kidneys become less efficient at filtering waste products, including phosphate. Sevelamer helps manage the phosphate levels, which is important because high phosphate levels can contribute to bone and heart problems in people with CKD.
• Dialysis: Sevelamer can be used for patients on both hemodialysis (using a machine to filter blood) and peritoneal dialysis (using fluid exchange within the abdomen for filtration).

Dosage and Administration:

• Tablet or Powder: Sevelamer comes in tablet or powder form, typically taken with meals.
• Dosage adjustment: The doctor will determine the appropriate dosage based on individual needs and blood phosphate levels.