Sodium aurothiomalate

Sodium aurothiomalate is a medication used to treat the symptoms of rheumatoid arthritis. It works by decreasing inflammation in the body and slowing down the progression of the disease. It is typically administered as an injection, and it can take several weeks to months for the full effects to be realized. Common side effects include nausea, vomiting, and skin rash.

Sodium aurothiomalate, also known as gold sodium thiomalate in the US, is a medication used primarily to manage rheumatoid arthritis. Here's a closer look at its properties:

Function:

• Disease-modifying antirheumatic drug (DMARD): Slows the progression of rheumatoid arthritis by dampening the overactive immune response that attacks joints [Mayo Clinic, DMARD].

Mechanism of Action:

• The exact mechanism isn't fully understood, but it's believed to involve:
  • Suppressing the immune system's activity [National Library of Medicine, Sodium Aurothiomalate]
  • Reducing inflammation in the joints

Administration:

• Given intramuscularly (injection into a muscle) typically once or twice a week.

Important Points:

• Primarily used for moderate to severe rheumatoid arthritis when other medications haven't been effective.
• May also be used to treat some cases of tuberculosis.
• Slow to take effect: Benefits may take several weeks or months to become noticeable.
• Close monitoring by a doctor is necessary due to potential side effects.

Potential Side Effects:

• Skin rash (most common)
• Mouth sores
• Kidney problems
• Bone marrow suppression
• Gastrointestinal problems (nausea, diarrhea)

Alternatives:

• Other DMARDs or biologic medications may be used if sodium aurothiomalate isn't tolerated or isn't effective.