Strontium ranelate is a medicine that is used to treat osteoporosis in adults. It works by increasing bone mass and improving bone strength, making bones less likely to break. It is usually taken twice a day with a glass of water. Side effects may include nausea, stomach pain, and diarrhea.
Strontium ranelate is a medication used to treat osteoporosis, a condition that weakens bones and makes them more prone to fractures. Here's a breakdown of its key aspects:
What it is:
- A strontium salt combined with ranelic acid.
- Marketed under brand names like Protelos or Protos.
What it does:
- Works uniquely by both stimulating new bone formation by osteoblasts and reducing bone breakdown by osteoclasts. This dual action is why it's called a "dual action bone agent" (DABA).
- Studies suggest it might also slow the progression of osteoarthritis in the knee.
Uses:
- Primarily prescribed for postmenopausal women with severe osteoporosis who are at high risk of fractures.
- Can be an option for men with osteoporosis as well, particularly if other osteoporosis medications aren't suitable.
- Its effectiveness in reducing vertebral and hip fractures in high-risk postmenopausal women is supported by research.
Important points to consider:
- Not approved for use in the United States by the FDA.
- Available as a prescription medication in over 70 countries.
- Taken orally.
Strontium Ranelate Granules
Strontium Ranelate Granules are a specific form of the medication strontium ranelate used to treat osteoporosis. Here's a breakdown of what they are and how they work:
What they are:
- Small granules containing strontium ranelate that come in individual sachets.
- Mixed with water to create a suspension before drinking.
How they work:
- Same mechanism of action as strontium ranelate - works by stimulating new bone formation and reducing bone breakdown.
- This dual action helps strengthen bones and reduces the risk of fractures, especially in the spine and hips, for people with osteoporosis.
How they are taken:
- Typically taken once daily at bedtime, on an empty stomach (at least two hours after eating or drinking milk).
- The granules are mixed with at least 30ml of water and consumed immediately after preparation.
Things to consider:
- This medication is intended for long-term use under a doctor's supervision.
- It's not a first-line treatment for osteoporosis and is usually prescribed when other options are not suitable.
- Strontium Ranelate Granules are not available in the United States but might be prescribed in some other countries.
Important safety information (not a substitute for professional medical advice):
- There can be potential side effects like nausea, diarrhea, and skin reactions.
- It's crucial to talk to your doctor about any pre-existing medical conditions or medications you are taking as there can be interactions.