Sucrose Octaacetate

Functional Category

Alcohol denaturant; bittering agent

Applications in Pharmaceutical Formulation

Sucrose octaacetate is used as an alcohol denaturant in pharmaceutical formulations. It is also used as a bittering agent, and is incorporated into preparations intended to deter nail-biting or thumb-sucking.

Description

Sucrose octaacetate occurs as white hygroscopic powder. It is practically odorless with a bitter taste.

Stability and Storage Conditions

Sucrose octaacetate is a stable material and should be stored in a well-closed, airtight container. Store in a cool, dry place; moisture may cause instability.
 

Safety

Sucrose octaacetate is generally regarded as safe. It is considered slightly hazardous in cases of skin contact (irritant), ingestion, or inhalation. LD50 (rabbit, skin): >5 g/kg LD50 (rat, oral): >5 g/kg(3)

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