Functional Category
Diluent; emollient; emulsifying agent; solvent; tablet binder.
Applications in Pharmaceutical Formulation
Sunflower oil is widely used as an edible oil, primarily in oleomargarine. It is also used extensively in cosmetics and pharmaceutical formulations. Therapeutically, sunflower oil is used to provide energy and essential fatty acids for parenteral nutrition. Studies have shown that sunflower oil may be used in intramuscular injections without inducing tissue damage.(1)
Description
Sunflower oil occurs as a clear, light yellow-colored liquid with a bland, agreeable taste.
Stability and Storage Conditions
Sunflower oil should be stored in an airtight, well-filled container, protected from light. Stability may be improved by the addition of an antioxidant such as butylated hydroxytoluene.
Incompatibilities
The oxidative stability of sunflower oil is reduced in the presence of iron oxides and zinc oxide.(2) Sunflower oil forms a ‘skin’ after being exposed to air for 2–3 weeks
Safety
Sunflower oil is widely used in food products and on its own as an edible oil. It is also used extensively in cosmetics and topical pharmaceutical formulations, and is generally regarded as a relatively nontoxic and nonirritant material.