Telotristat is a prescription medication used to reduce the production of serotonin in adults with carcinoid syndrome diarrhea. It works by inhibiting the enzyme tryptophan hydroxylase, which helps to reduce the amount of serotonin being produced in the body. Telotristat is usually taken in combination with other medications to help control symptoms of carcinoid syndrome. The most common side effects of telotristat include headache, nausea, and abdominal pain.
Telotristat is a medication used in combination with another medication (a somatostatin analog) to control diarrhea caused by carcinoid tumors (slow-growing tumors that release natural substances that can cause symptoms like diarrhea) in patients with diarrhea not controlled by a somatostatin analog alone. It works by blocking the formation of a certain natural substance in the body (serotonin) that is released by the carcinoid tumors and causes diarrhea.
Here are some other things to know about Telotristat:
- It comes as a tablet taken by mouth, usually three times a day with food.
- The most common side effects of Telotristat are abdominal pain, increased gamma-glutamyl transferase levels, and fatigue.
- Telotristat can interact with other medications, so it is important to tell your doctor about all the medications you are taking before starting Telotristat.
- Telotristat should not be used by pregnant women or women who are breastfeeding.