Teneligliptin

Teneligliptin is an oral anti-diabetic medication used to treat type 2 diabetes. It works by increasing the amount of insulin released by the pancreas, helping the body to better control blood sugar levels. It may also help to reduce the amount of sugar absorbed from the diet, helping to reduce overall sugar intake. Teneligliptin is usually taken once or twice a day, with or without food. It is important to take it as prescribed, as stopping the medication without consulting your doctor may cause the diabetes to worsen.

Teneligliptin is a medication used to manage a chronic condition: type 2 diabetes mellitus (T2DM) in adults. Here's a closer look at its role in diabetes management:

Function:

  • Belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors, also known as gliptins.
  • Doesn't directly lower blood sugar but helps regulate the body's natural blood sugar control mechanisms.

Mechanism of Action:

  • Works by inhibiting the DPP-4 enzyme.
  • DPP-4 is an enzyme that breaks down hormones called incretins, like GLP-1 (glucagon-like peptide-1).
  • Incretins play a role in stimulating insulin release from the pancreas after a meal and suppressing glucagon secretion, a hormone that raises blood sugar levels.
  • By inhibiting DPP-4, Teneligliptin allows higher levels of incretins to circulate, promoting insulin release and reducing glucagon release.
  • This combined effect helps improve blood sugar control in individuals with T2DM.

Use:

  • Prescribed either alone (monotherapy) or more commonly, combined with other diabetes medications like metformin, to improve glycemic control (blood sugar management) in adults with T2DM when diet and exercise alone are not sufficient.

Administration:

  • Taken orally as tablets, typically once a day.

Side Effects:

  • Generally well-tolerated, but common side effects can include headache, upper respiratory tract infections, and urinary tract infections.
  • In rare cases, more serious side effects like allergic reactions or pancreatitis (inflammation of the pancreas) may occur.
Anatomical Therapeutic Chemical Classification
A - Alimentary tract and metabolism
A10 Drugs used in diabetes
A10B - Blood glucose lowering drugs, excluding insulins
A10BH Dipeptidyl peptidase 4 (DPP-4) inhibitors
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