Terguride

Terguride is a medication used for the treatment of prostate enlargement (benign prostatic hyperplasia). It works by reducing the levels of hormones that cause the enlargement of the prostate. It can also help to reduce the risk of urinary retention and the need for surgery. Terguride can also be used to treat symptoms associated with prostate cancer, such as urinary urgency, frequency, and nocturia.

Terguride is a medication belonging to the ergoline family that acts on both dopamine and serotonin receptors [Wikipedia: Terguride]. Here's a breakdown of its key aspects:

Main Uses:

• Primarily used in Japan as a prolactin inhibitor for treating hyperprolactinemia (condition with high prolactin levels) [Wikipedia: Terguride]. Prolactin is a hormone involved in milk production and can disrupt menstrual cycles or fertility in some cases [Mayo Clinic: Hyperprolactinemia].
• Taken orally.

How it Works:

• Acts as a dopamine receptor agonist, mimicking dopamine's effects to lower prolactin production [Wikipedia: Terguride].
• Also has some serotonin receptor antagonist activity, but crucially, it doesn't target the specific serotonin receptor linked to heart valve problems (5-HT2B) [Wikipedia: Terguride].

Advantages:

• Compared to some other medications for hyperprolactinemia, terguride might have a lower risk of side effects [PubMed: Terguride--a new dopamine agonist drug].

Things to Consider:

• Terguride is not widely available globally and its use is primarily concentrated in Japan [Wikipedia: Terguride].
• As with any medication, consult a doctor before starting terguride to discuss potential side effects and interactions with other medications you might be taking.

Additional Information:

• Brand name: Teluron (Japan) [Wikipedia: Terguride]
• Other names: Dironyl, Mysalfon, trans-Dihydrolisuride [Wikipedia: Terguride]