Tibolone is a synthetic hormone therapy used to treat the symptoms of menopause. It works by mimicking the action of the hormones estrogen, progesterone, and testosterone. It can be used to treat hot flashes, night sweats, vaginal dryness, and other menopausal symptoms. Tibolone may also help to prevent thinning of the bones and reduce the risk of osteoporosis. Common side effects of tibolone include headaches, nausea, breast tenderness, and irregular or breakthrough bleeding.
Tibolone is a medication used in menopausal hormone therapy (HRT) and in the treatment of postmenopausal osteoporosis . It is sold under the brand name Livial among others.
Tibolone is a synthetic steroid that has weak estrogenic, progestogenic, and androgenic effects. This means it acts similarly to the hormones estrogen, progesterone, and testosterone in the body.
Here's a summary of how tibolone works:
- Estrogenic effects: Tibolone helps to reduce hot flashes, improve vaginal atrophy and urogenital symptoms (e.g., vaginal dryness, dyspareunia), and has positive effects on mood and sexual function.
- Progestogenic effects: Tibolone helps to protect the lining of the uterus (endometrium) from thickening too much, which is a risk factor for endometrial cancer.
- Androgenic effects: Tibolone may have greater benefits on libido than standard menopausal hormone therapy, and this is likely due to its androgenic effects.