Trichloroethylene is a solvent used in a variety of industrial and commercial applications, including dry cleaning, metal degreasing, and adhesives. It is also used medically as a sedative and anesthetic. Trichloroethylene is a colorless liquid with a sweet smell. It is flammable and exposure can lead to irritation of the eyes, skin, and upper respiratory tract. Long-term exposure to trichloroethylene is linked to an increased risk of cancer and other health effects.
Trichloroethylene (TCE) is not a currently recommended medical substance. While it has a history of use in medicine, it's no longer considered safe due to health risks. Here's a breakdown of TCE:
Historical Medical Use:
- Trichloroethylene was once used as a general inhalational anesthetic, particularly during childbirth and for trigeminal neuralgia (severe facial pain) in the past.
- This use has been discontinued due to the availability of safer alternatives and the discovery of its hazardous properties.
Health Risks:
- TCE is classified as a known carcinogen (cancer-causing agent) by multiple agencies.
- Exposure to TCE has been linked to various health problems, including:
- Kidney cancer
- Liver cancer
- Non-Hodgkin's lymphoma
- Central nervous system depression (dizziness, headache, confusion)
- Respiratory irritation
- Birth defects (with long-term maternal exposure)
Current Status:
- TCE is primarily used as an industrial solvent for degreasing metals and in refrigerants.
- Regulations limit occupational exposure due to its health risks.
- TCE exposure can also occur through contaminated drinking water sources.
Anatomical Therapeutic Chemical Classification
N - Nervous system
N01 Anesthetics
N01A - Anesthetics, general
N01AB Halogenated hydrocarbons
ATC Code
External Links
Trichloroethylene