Umifenovir, also known as Arbidol, is an antiviral medication used to treat certain viral infections such as influenza and the common cold. It blocks the attachment of the virus to the cell and inhibits the replication of the virus. It is generally well tolerated and is available as an oral suspension or tablet. It is sometimes used in combination with other medications to treat more severe infections.
Umifenovir, also sold under the brand name Arbidol, is an antiviral medication primarily used in Russia and China for treating influenza and some COVID-19 infections. Here's a breakdown of key points about Umifenovir:
- Uses: Treatment and prophylaxis (prevention) of influenza and potentially COVID-19 (investigational use).
- Mechanism of Action: It acts in two ways:
- Directly targeting the virus and inactivating it (virucidal effect).
- Inhibiting the virus's ability to enter host cells (by preventing membrane fusion).
- Important Note: Umifenovir is not approved by the U.S. Food and Drug Administration (FDA) for treatment or prevention of influenza or COVID-19.
- Other Considerations:
- Umifenovir has been around for over 25 years in Russia and since 2006 in China.
- Research is ongoing to determine its effectiveness against COVID-19.
- It has shown some promise in modulating the immune system in addition to its antiviral effects.
Anatomical Therapeutic Chemical Classification
J - Antiinfectives for systemic use
J05 Antivirals for systemic use
J05A - Direct acting antiviral drugs
J05AX Other antivirals
ATC Code
External Links
Umifenovir